Oxygen and Glucose Transportation and Distribution on 3D Osteochondral Scaffold in Silico Model

Nutrients supply especially like nutrients and oxygen play vital role in tissue engineering process. It is found that could not grow very well the middle of scaffold because few transport to middle. Nutrient limitations would reduce cell proliferation differentiation. In case, there urgent need understand nutrient distribution for both vitro vivo study, as no technology able researchers observe during those this paper, a numerical model coupling with VOF (volume fluid) species together predicting glucose after implantation site developed. Comparing our previous tests, regenerated has similar trend rather than glucose. The reported manufactured by additive manufacturing provided good interconnected structure which facilitated transportation scaffold. Considering transportation, be used better understanding scaffold, leading formation